Prevalence and Antibiotic Resistance Patterns of Bacterial Isolates from Urine Samples of Patients Attending Kwara State Civil Service Hospital Ilorin, Nigeria

Abstract

Antibiotic resistance has become alarming throughout the world and most especially in third world countries in particular. Human urine samples(n= 80) of patients attending the Kwara state Civil Service Hospital Ilorin, North Central Nigeria were analysed for Urinary Tract Infections(UTIs) and Antibiotic Susceptibility pattern of isolated organisms. The urine samples were cultured on blood agar, MacConkey agar and Cysteine lactose electrolyte deficient (CLED) agar while antimicrobial susceptibility test was determined using Kirby-Bauer disc diffusion method. The following bacteria were isolated Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, Proteus mirabilis, Staphylococcus epidermidis, Enterococcus faecalis and Klebsiella pneumoniae. The isolates comprise of 57.1% Gram negative bacteria and 42.9% Gram positive bacteria. This study revealed that antibiotics such as Ciprofloxacin and Ofloxacin(100% and 71.4% susceptibility respectively) are the most effective against the isolates, the antibiotic resistance pattern of the isolates indicates emerging multi drug resistance among urinary tract bacterial pathogens.