Serum urea and creatinine levels in pregnant women attending Antenatal clinic in General Hospital Suleja- Niger state

Abstract

Levels of renal function parameters (urea and creatinine) were assessed in normal pregnant women attending General Hospital Suleja- Niger State in order to identify the association between these biochemical parameter and gestation period (first, second and third trimester) compared to those of normal non- pregnant women as a control. A total of 200 women were participating in the study, they include 150 pregnant women and 50 non-pregnant women. The result obtained showed a significant (p<0.05) lower value in mean serum urea level in the pregnant group during the 3^rd trimester of the pregnancy, while the mean value of urea show a non significant (p<0.05) decrease through out the 1^st and 2^nd trimester of the pregnancy when compared with the control group. There was a significant difference in serum creatinine between the 1^st and 3^rd trimester, which were higher in the 3^rd trimester than in the 1^st and 2^nd tirmester of the pregnancy, but no significant difference in serum creatinine between 1^st and 2^nd trimester of the pregnancy when compared with the control group. All these changes could be due to physiological adaptations of the mother to the growing fetus.